On October 28, a research team led by Zhang Xiaheng at the Hangzhou Institute for Advanced Studies, University of Chinese Academy of Sciences (HICAS) published a study titled "Direct deaminative functionalization with N-nitroamines" in the journal Nature.

Details:

The study innovatively proposed a "direct deamination" strategy, enabling efficient and safe transformation of aromatic amines. As aromatic amines serve as fundamental structural units in most drug formulations, this breakthrough opens a more economical and environmentally friendly technical pathway for synthesizing medications such as anti-cancer drugs. The research team has already entered into collaboration with a manufacturer of anti-cancer drug intermediates. Preliminary estimates from the company indicate that adopting this new process is expected to significantly reduce costs.

(Source: Zhejiang Daily)